J. Skinner

MAARU: Multichannel Acoustic Autonomous Recording Unit for spatial ecosystem monitoring.

The paper introduces MAARU, a low-cost, open-source multichannel acoustic recorder for spatial ecosystem monitoring, demonstrating its accuracy in localizing sounds and improving species identification.

Broadly neutralizing antibodies target the coronavirus fusion peptide

The paper identifies six monoclonal antibodies that broadly neutralize coronaviruses by targeting the conserved fusion peptide.

Distinct subpopulations of DN1 thymocytes exhibit preferential γδ T lineage potential

This study identifies distinct DN1 thymocyte subpopulations with preferential γδ T lineage potential using scRNA-seq in mice.

Atypical B cells upregulate co-stimulatory molecules during malaria and secrete antibodies with T follicular helper cell support

This study shows that atypical B cells actively respond to acute malaria and have the capacity to produce antibodies with T cell help.

Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants

This study identifies ultrapotent bispecific antibodies that neutralize emerging SARS-CoV-2 variants by targeting multiple spike protein regions, showing efficacy in vitro and in a hamster model.

Novel EGFRvIII-CAR transgenic mice for rigorous preclinical studies in syngeneic mice

This paper develops a novel transgenic mouse model expressing EGFRvIII-CAR on T-cells to study CAR T-cell therapy in syngeneic glioblastoma models.

Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype

This paper shows that repeated Plasmodium falciparum infections reprogram human monocytes to a regulatory phenotype, reducing inflammatory responses during subsequent infections.

Plasmodium falciparum-specific IgM B cells dominate in children, expand with malaria and produce parasite inhibitory IgM

The paper identifies Pf-specific IgM B cells in children, showing they expand during malaria and produce inhibitory IgM antibodies.