Author

M. Chambers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:differential expression· 1

Frequent Co-Authors

A. B. McDermott· 2 shared X. Chen· 2 shared A. Diouf· 1 shared A. Druz· 1 shared A. F. Zhou· 1 shared A. J. Jafari· 1 shared A. Ongoiba· 1 shared A. P. Rowshan· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

A. B. McDermott

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

SON-dependent nuclear speckle rejuvenation alleviates proteinopathies

W. Dion, Y. Tao, M. Chambers, S. Zhao, R. K. Arbuckle, M. Sun, S. Kubra, M. Schaich, Y. Nie, M. Ye, I. Jamal, M. B. Larsen, D. Camarco, E. Ickes, H. Wang, , B. Zhu

This study identifies pyrvinium pamoate as a compound that rejuvenates nuclear speckles, improving protein quality control and reducing YAP1 activity, thereby alleviating proteinopathies in pre-clinical models.

bioRxiv · Apr 18, 2024Cell Biology

Variation in drug penetration does not account for the natural resistance of Mycobacterium abscessus biofilms to antibiotic

W. C. Akwani, P. Rakowska, I. Gilmore, M. Chambers, G. McMahon, S. Hingley-Wilson

This study investigates antibiotic susceptibility in M. abscessus biofilms and finds that reduced efficacy is not due to differences in antibiotic penetration but may involve other biofilm characteristics.

bioRxiv · Apr 16, 2024 · PreprintMicrobiology

Plasmodium falciparum-specific IgM B cells dominate in children, expand with malaria and produce parasite inhibitory IgM

C. Hopp, A. Diouf, K. Miura, K. Boswell, P. Sekar, J. Skinner, C. M. Tipton, M. Chambers, S. Andrews, J. Tan, S. Li, S. Doumbo, K. Kayentao, A. Ongoiba, B. Traore, , P. D. Crompton

The paper identifies Pf-specific IgM B cells in children, showing they expand during malaria and produce inhibitory IgM antibodies.

bioRxiv · Apr 12, 2020Immunology

Outflanking Immunodominance to Target Subdominant Broadly Neutralizing Epitopes

D. Angeletti, I. Kosik, W. T. Yewdell, C. M. Boudreau, V. V. Mallajosyula, M. Chambers, M. Prabhakaran, H. D. Hickman, A. B. McDermott, G. Alter, J. Chaudhuri, J. W. Yewdell

This study shows that immunodominance in influenza HA can be overcome by targeting the conserved stem through specific immunization strategies.

bioRxiv · Jun 14, 2018Immunology

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

K. Xu, P. Acharya, R. Kong, C. Cheng, G.-Y. Chuang, K. Liu, M. K. Louder, S. O Dell, R. Rawi, M. Sastry, C.-H. Shen, B. Zhang, T. Zhou, M. Asokan, R. T. Bailer, , McDermott

This study shows that targeting the HIV-1 fusion peptide with specific immunogens induces cross-clade neutralizing antibodies in animals.

bioRxiv · Apr 23, 2018Immunology