Author

C. J. Buchholz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Braun· 1 shared A. Jamali· 1 shared A. Michels· 1 shared E. Adabi· 1 shared E. Flory· 1 shared F. Thalheimer· 1 shared K. Cichutek· 1 shared N. Ho· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Braun

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintNov 12, 2022

Early induction of severe cytokine release syndrome by rapidly generated CAR T cells in a preclinical mouse model

N. Ho, A. Jamali, A. Braun…·C. J. Buchholz

This study shows that rapidly generated CAR T cells induce severe cytokine release syndrome in a mouse model within 24 hours.

DOI 10.1101/2022.11.12.515207

mousebulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivOct 15, 2020

Quantitative Assays Reveal Cell Fusion at Minimal Levels of SARS-CoV-2 Spike Protein and Fusion-from-Without

S. A. Theuerkauf, A. Michels, V. Riechert…·C. J. Buchholz

The paper develops quantitative assays to study SARS-CoV-2 spike protein-mediated cell fusion, revealing that syncytia formation can occur at low S protein levels and is less inhibited by antibodies than particle-cell fusion.

DOI 10.1016/j.isci.2021.102170

humanproteomics

𝕏 PostBluesky