Author

C. Jeans

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Kimberlin· 1 shared A. Seth· 1 shared A. Wozniak· 1 shared D. F. Savage· 1 shared D. L. Parton· 1 shared E. Applegate· 1 shared E. C. Stahl· 1 shared J. A. Doudna· 1 shared

Activity by Year

2016-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioengineering

A. Kimberlin

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Author profile →

2 papers

Recent·Most cited

Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs

E. C. Stahl, J. K. Sabo, M. H. Kang, R. Allen, E. Applegate, S. E. Kim, Y. Kwon, A. Seth, N. Lemus, V. Salinas-Rios, K. Soczek, M. Trinidad, L. T. Vo, C. Jeans, A. Wozniak, , J. A. Doudna

This study demonstrates that minimally immunogenic Cas9 RNPs delivered via convection enhanced delivery can edit mouse striatal neurons with reduced immune responses compared to AAV-delivered Cas9.

bioRxiv · Apr 13, 2023Bioengineering

An open library of human kinase domain constructs for automated bacterial expression

S. K. Albanese, D. L. Parton, M. Isık, L. Rodriguez-Laureano, S. M. Hanson, J. M. Behr, S. Gradia, C. Jeans, N. M. Levinson, M. A. Seeliger, J. D. Chodera

This paper presents a library of 52 human kinase domain constructs expressed in bacteria using phosphatase coexpression, enabling high-throughput biochemical and biophysical studies.

bioRxiv · Feb 25, 2016Biochemistry