Cancer BiologybioRxiv
PRMT1 is a critical dependency in clear cell renal cell carcinoma through its role in post-transcriptional regulation of DNA damage response genes
DOI 10.1038/s41467-024-52507-y
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2 papers
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Y. Yang, J. Ahn, N. J. Edwards…·R. Goldman
The paper investigates SULF1 and SULF2 in HNSC and other cancers, finding SULF1 is secreted by fibroblasts and negatively impacts survival early, while SULF2, from tumor cells, affects survival later, with implications for therapy.