Author

C. Kessler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:E. coli· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

W. Kim· 2 shared A. J. Lloyd· 1 shared A. Shafer· 1 shared C. E. Rowland· 1 shared C. G. Dowson· 1 shared D. Bellini· 1 shared D. I. Roper· 1 shared E. Mhatre· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

W. Kim

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Discovery and chemical optimisation of a Potent, Bi-cyclic (Bicycle(R)) Antimicrobial Inhibitor of Escherichia coli PBP3

C. E. Rowland, H. Newman, T. T. Martin, R. Dods, N. Bournakas, J. M. Wagstaff, N. Lewis, S. J. Stanway, M. Balmforth, C. Kessler, K. van Rietschoten, D. Bellini, D. I. Roper, A. J. Lloyd, C. G. Dowson, , M. J. Dawson

This study discovers and optimizes bicyclic peptide inhibitors of E. coli PBP3, showing high-affinity binding and broad-spectrum antimicrobial activity.

bioRxiv · Mar 20, 2024 · PreprintBiochemistry

Natural products from food sources can alter the spread of AMR plasmids in Enterobacterales

I. Alav, P. Pordelkhaki, J. Rodriguez Navarro, O. Neo, C. Kessler, R. J. Awodipe, P. Cliffe, H. Marton, S. Gibbons, M. M. C. Buckner

The paper shows natural products can reduce AMR plasmid transmission in Enterobacterales, with rottlerin being particularly effective against K. pneumoniae.

bioRxiv · Feb 26, 2024 · PreprintMicrobiology

Identification of cyclic-di-GMP-modulating protein residues by bi-directionally evolving a social trait in Pseudomonas fluorescens

C. Kessler, W. Kim

This study identifies c-di-GMP-modulating residues in Pseudomonas fluorescens by evolving social traits and analyzing mutations affecting c-di-GMP production.

bioRxiv · May 10, 2022 · PreprintMicrobiology

Speciation without gene-flow in hybridising deer

C. Kessler, E. Wootton, A. Shafer

This study examines speciation in hybridising deer species, finding no historical gene flow and instead detecting balancing selection related to immunity and sensory perception.

bioRxiv · Apr 20, 2022Evolutionary Biology

Evolutionary divergence of the Wsp signal transduction system in β- and γ-proteobacteria

C. Kessler, E. Mhatre, V. S. Cooper, W. Kim

This study shows the Wsp system is conserved across β- and γ-proteobacteria, with functional differences in Burkholderia cenocepacia compared to Pseudomonas species.

bioRxiv · Jul 2, 2021Microbiology