Author

C. Kuscu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Bajwa· 1 shared A. Dutta· 1 shared A. H. Habieb· 1 shared A. Stayton· 1 shared C. Brown· 1 shared C. Watkins· 1 shared C. White· 1 shared D. Liu· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

A. Bajwa

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Exogenous mitochondrial transfer increases energy expenditure and attenuates adiposity gains in mice with diet-induced obesity

M. Namwanje, S. Mazumdar, A. Stayton, P. S. Patel, C. Watkins, C. White, C. Brown, J. D. Eason, K. Mozhui, C. Kuscu, N. Pabla, E. J. Stephenson, A. Bajwa

This study shows that transferring mitochondria from lean mice to obese mice increases energy expenditure, reduces adiposity, and improves metabolic health.

bioRxiv · Dec 23, 2023 · PreprintPhysiology

Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells

X. Wei, J. Yang, S. J. Adair, C. Kuscu, K. Y. Lee, W. Kane, P. E. O'Hara, D. Liu, Y. M. Demirlenk, A. H. Habieb, E. Yilmaz, A. Dutta, T. Bauer, M. Adli

The paper identifies PRMT5 as a synthetic lethal target with gemcitabine in pancreatic cancer using CRISPR screening in a PDX model.

bioRxiv · May 25, 2020Cancer Biology