T. Bauer

Activation of three targets by a TAL effector confers susceptibility to bacterial blight of cotton

The paper identifies a newly evolved TALE, Tal7b, that activates multiple GhSWEET genes in cotton, contributing to bacterial blight susceptibility.

Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege

This study shows that EGFR protects hair follicle stem cells from immune-mediated damage by maintaining JAK-STAT1-sensitive immune privilege, and its disruption leads to scarring hair loss, which can be reversed by JAK1/2 inhibition.

Deep molecular characterization linked to drug response profiling of pancreatic ductal adenocarcinoma using patient-derived organoids.

This study uses patient-derived PDAC organoids to integrate genomic, transcriptomic, and drug response data, identifying novel biomarkers and resistance mechanisms for personalized treatment.

Cutibacterium acnes clonal complexes display various growth rates in blood culture bottles used for diagnosing orthopedic device related infections

This study examines growth rates of Cutibacterium acnes clonal complexes in blood culture bottles, finding CC53 grows faster than other complexes in clinical settings.

Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells

The paper identifies PRMT5 as a synthetic lethal target with gemcitabine in pancreatic cancer using CRISPR screening in a PDX model.