Microbial metabolite butyrate-prodrug polymeric micelles demonstrate therapeutic efficacy in pre-clinical models of food allergy and colitis
R. Wang, S. Cao, M. E. H. Bashir, L. A. Hesser, Y. Su, S. M. C. Hong, A. Thompson, E. Culleen, M. Sabados, N. P. Dylla, E. Campbell, R. Bao, E. B. Nonnecke, C. L. Bevins, D. S. Wilson, , C. R. Nagler
The paper develops butyrate-prodrug polymeric micelles that restore gut barrier function and reduce inflammation in pre-clinical models of food allergy and colitis.
bioRxiv · May 1, 2022Bioengineering