J. A. Hubbell

This study develops a butyrate prodrug, SerBut, which improves oral bioavailability and reduces autoimmune arthritis and neuroinflammation in mouse models.

This study shows that conjugating immunogenic biologics to a synthetic mannose polymer reduces anti-drug antibody responses by impairing T cell and B cell responses.

This paper develops a glycosylation-modified antigen vaccine platform that prevents anaphylaxis in a cow's milk allergy mouse model by inducing antigen-specific non-responsiveness.

The paper develops butyrate-prodrug polymeric micelles that restore gut barrier function and reduce inflammation in pre-clinical models of food allergy and colitis.

Blocking antibodies against integrins-3, -M, and -Mβ2 reverse lung and kidney fibrosis in a mouse model by de-differentiating myofibroblasts.

This paper demonstrates that conjugating the SARS-CoV-2 Spike protein to a polymeric glyco-adjuvant elicits strong cellular and humoral immune responses in mice.

This study shows laminin heparin-binding peptides bind growth factors and enhance diabetic wound healing by acting as GF reservoirs and cell scaffolds.