Cell BiologybioRxivPreprint
Human alveolar Type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells during alveolar repair
J. J. Kathiriya, C. Wang, A. Brumwell…·T. Peng
This study shows human alveolar type 2 cells can transdifferentiate into KRT5+ basal cells in 3D organoids, a process linked to IPF pathology and not observed in murine cells.