Author

M. Matthay

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 5 Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. J. Combes· 2 shared A. Shen· 2 shared C. Wang· 2 shared D. Sheppard· 2 shared L. Rodriguez· 2 shared M. Cassandras· 2 shared P. Wolters· 2 shared T. Peng· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. J. Combes

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Myeloid-mesenchymal crosstalk drives Arg1-dependent profibrotic metabolism via ornithine in lung fibrosis

P. Yadav, J. Gomez Ortega, P. Dabral, W. Tamaki, C. Chien, K.-C. Chang, N. Biswas, S. Pan, J. Nilsson, X. Yin, A. Bhattacharyya, K. Boostanpour, T. Jujaray, J. Wang, T. Tsukui, , M. Bhattacharya

The paper identifies a myeloid-mesenchymal crosstalk pathway involving Arg1 and ornithine that drives profibrotic metabolism in lung fibrosis.

bioRxiv · Sep 6, 2023Immunology

SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator

L. Hysenaj, S. Little, K. R. Kulhanek, O. Gbenedio, L. Rodriguez, A. Shen, J.-C. Lone, L. C. Lupin-Jimenez, L. Bonser, N. K. Serwas, K. Bahl, E. Mick, J. Z. Li, V. Ding, S. Matsumoto, , J. P. Roose

The paper identifies TSPAN8 as a novel mediator of SARS-CoV-2 infection in lung organoids, showing its correlation with infection rates and susceptibility to blocking antibodies.

bioRxiv · Jun 1, 2021 · PreprintMicrobiology

Global Absence and Targeting of Protective Immune States in Severe COVID-19.

A. J. Combes, T. Courau, N. F. Kuhn, K. H. Hu, A. Ray, W. S. Chen, S. J. Clearly, N. W. Chew, D. Kushnoor, G. C. Reeder, A. Shen, J. Tsui, K. J. Hiam-Galvez, P. Munoz-Sandoval, W. S. Zhu, , M. F. Krummel

The paper identifies that severe COVID-19 patients lack ISG-expressing cells and have antibodies that block their production, contrasting with mild cases.

bioRxiv · Oct 28, 2020Immunology

Human alveolar Type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells during alveolar repair

J. J. Kathiriya, C. Wang, A. Brumwell, M. Cassandras, C. Le Saux, P. Wolters, M. Matthay, H. A. Chapman, T. Peng

This study shows human alveolar type 2 cells can transdifferentiate into KRT5+ basal cells in 3D organoids, a process linked to IPF pathology and not observed in murine cells.

bioRxiv · Jun 6, 2020 · PreprintCell Biology

Gli1+ mesenchymal stromal cells modulate epithelial metaplasia in lung fibrosis

M. Cassandras, C. Wang, J. Kathiriya, T. Tsukui, P. Matatia, M. Matthay, P. Wolters, A. Molofsky, D. Sheppard, H. Chapman, T. Peng

This study shows Gli1+ mesenchymal stromal cells drive metaplastic differentiation of airway progenitors into KRT5+ basal cells in fibrosis by modulating BMP activation through hedgehog signaling.

bioRxiv · Nov 14, 2019Cell Biology