Innate immune cell-intrinsic ketogenesis is dispensable for organismal metabolism and age-related inflammation
E. L. Goldberg, A. Letian, T. Dlugos, C. Leveau, V. D. L. Dixit
This study shows that ketogenesis in innate immune cells is not essential for metabolism or age-related inflammation, but liver-derived ketone bodies are critical for controlling inflammation and metabolism during aging.
bioRxiv · Oct 14, 2022Immunology