Author

M. Bernard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Microbiology· 2 Cancer Biology· 1 Cell Biology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 10 Research Focus:cell type annotation· 5 Organism:human· 5 Assay:bulk RNA-seq· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:differential expression· 3 Research Focus:host-pathogen & immune response· 3

Frequent Co-Authors

G. Le Lay· 2 shared P. MARULLO· 2 shared P. Vargas· 2 shared A. Al-Janadi· 1 shared A. Chatelier· 1 shared A. Dagenais· 1 shared A. Delafenetre· 1 shared A. Delcourt· 1 shared

Activity by Year

2017-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 5 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

G. Le Lay

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

DMD Human iPSC-derived skeletal muscle cells recapitulate selective calcium dysregulation pathways.

A. Delafenetre, C.-A. Chapotte-Baldacci, L. Doremus, E. Massourides, M. Bernard, M. Regnacq, J. Piquereau, A. Chatelier, C. Cognard, C. Pinset, S. Sebille

This study examines DMD patient-derived iPSC skeletal muscle cells, finding unique calcium dysregulation patterns not fully replicated in animal models.

bioRxiv · Jan 20, 2024 · PreprintCell Biology

Interleukin-10-producing monocytes contribute to sex differences in pain resolution in mice and humans.

J. Sim, E. O'Guin, K. Monahan, C. Sugimoto, S. McLean, L. Albertorio-Saez, Y. Zhao, A. Dagenais, S. Laumet, M. Bernard, J. K. Folger, A. J. Robison, S. D. Linnstaedt, G. Laumet

The paper shows that male mice and humans have higher IL-10-producing monocytes, which correlate with faster pain resolution, and that androgens drive this sex difference.

bioRxiv · Nov 3, 2023Immunology

Androgen receptor inhibition induces metabolic reprogramming and increased reliance on oxidative mitochondrial metabolism in prostate cancer

P. Crowell, J. Giafaglione, A. Jones, N. Nunley, T. Hashimoto, A. Delcourt, A. Petcherski, M. Bernard, R. R. Huang, J.-Y. Low, N. Matulionis, X. Guan, N. Navone, J. Alumkal, M. Haffner, , A. S. Goldstein

This study shows that androgen receptor inhibition in prostate cancer cells shifts metabolism to oxidative mitochondrial pathways and increases sensitivity to complex I inhibitors.

Cell Reports · Oct 1, 2023Peer-reviewedCancer Biology

Cyclosporin A delays the terminal disease stage in Tfam KO mice without improving mitochondrial energy production

B. Chatel, I. Varlet, A. Ogier, E. Pecchi, M. Bernard, J. GONDIN, H. Westerblad, D. Bendahan, C. Gineste

bioRxiv · Oct 14, 2022 · PreprintPathology

Actin dynamics regulation by TTC7A/PI4KIIIα axis limits DNA damage and cell death during leukocyte migration

T. Gajardo, M. Lo, M. Bernard, C. Leveau, M.-T. El-Daher, M. Kurowska, G. Le Lay, D. Moshous, B. Neven, A. Fischer, G. Menasche, G. de Saint Basile, P. Vargas, F. E. Sepulveda

This study shows TTC7A deficiency impairs leukocyte migration, leading to DNA damage and cell death during chemotaxis in dense environments.

bioRxiv · Oct 14, 2021 · PreprintImmunology

Enhancing c-MYC degradation via 20S proteasome activation induces in vivo anti-tumor efficacy

E. Njomen, T. Lansdell, A. Vanecek, V. Benham, M. Bernard, Y.-T. Yang, P. Schall, D. Isaac, O. Alkharabsheh, A. Al-Janadi, m. Giletto, E. Elsworth, C. Taylor, T. Yang, m. Bailie, , J. Tepe

This study shows that activating the 20S proteasome with small molecules reduces c-MYC-driven cancer growth in vitro and in vivo, including in bortezomib-resistant cells.

bioRxiv · Aug 24, 2020 · PreprintPharmacology & Toxicology

HIF2α is a Direct Regulator of Neutrophil Motility

S. Sormendi, M. Deygas, A. Sinha, A. Krueger, I. Kourtzelis, G. Le Lay, M. Bernard, P. Saez, M. Gerlach, K. Franke, A. Meneses, M. Kraeter, A. Palladini, J. Guck, U. Coskun, , B. Wielockx

This study identifies HIF2α as a regulator of neutrophil motility through the PHD2-HIF2-RhoA axis, enhancing migration in hypoxic environments during inflammation.

bioRxiv · Jun 5, 2020Immunology

The SSU1 checkup, a rapid tool for detecting chromosomal rearrangements of the Saccharomyces cerevisiae chromosome XVI. An ecological and technological study on wine yeast.

P. MARULLO, O. Claisse, M. L. Raymond Eder, N. Feghali, M. Bernard, J.-L. Legras, W. Albertin, A. L. Rosa, I. Masneuf-Pomarede

The paper develops a multiplex PCR method to rapidly detect three chromosomal rearrangements in Saccharomyces cerevisiae associated with sulfite tolerance and shows their environmental and commercial distribution.

bioRxiv · Apr 23, 2020Microbiology

Establishment of a pig influenza challenge model for evaluation of monoclonal antibody delivery platforms

A. McNee, T. Smith, B. Holzer, C. Becky, E. Bessell, G. Guibinga, H. Brown, K. Schultheis, P. Fisher, S. Ramos, A. Nunez, M. Bernard, V. Martini, T. Chrun, Y. Xiao, , E. Tchilian

This study establishes a pig influenza model to evaluate monoclonal antibody efficacy against H1N1, showing dose-dependent reduction in viral load and lung pathology.

bioRxiv · Mar 12, 2020Immunology

Wine yeast phenomics: a standardized fermentation method for assessing quantitative traits of Saccharomyces cerevisiae strains in enological conditions.

E. Peltier, M. Bernard, M. Trujillo, D. Prodhomme, J.-C. Barbe, Y. Gibon, P. Marullo

This paper develops a small-scale fermentation method to assess quantitative traits of Saccharomyces cerevisiae strains in enological conditions, showing it accurately captures kinetic parameters and metabolite production.

bioRxiv · Sep 20, 2017Microbiology