Author

P. Vargas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 5 Biophysics· 2 Immunology· 2 Biochemistry· 1 Pathology· 1

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Research Focus:cell signaling & trafficking· 5 Approach:experimental assay· 5 Organism:plant (other)· 5 Approach:statistical model· 5 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Assay:imaging· 3 Assay:whole-genome sequencing· 3

Frequent Co-Authors

M. Fernandez-Mazuecos· 3 shared M. Piel· 3 shared G. Le Lay· 2 shared I. Julca· 2 shared M. Bernard· 2 shared M. Marcet-Houben· 2 shared T. Gabaldon· 2 shared A. Fischer· 1 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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3 shared papersEvolutionary Biology

M. Fernandez-Mazuecos

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11 papers

Recent·Most cited

Phylogenetics and phylogeography of Euphorbia canariensis reveal an extreme Canarian-Asian disjunction and limited inter-island colonization

A. J. Coello, P. Vargas, E. Cano, R. Riina, M. Fernandez-Mazuecos

This study reconstructs the evolutionary history of Euphorbia canariensis, revealing a close relationship with Southeast Asian species and a west-to-east colonization pattern in the Canary Islands with limited inter-island dispersal.

Plant Biology · Mar 5, 2024Peer-reviewedEvolutionary Biology

The genomic basis of the plant island syndrome in Darwin's giant daisies

J. Cerca, B. Petersen, J. M. Lazaro Guevara, A. Rivera-Colon, S. Birkeland, J. Vizueta, S. Li, J. Loureiro, C. Kosawang, P. Jaramillo Diaz, G. Rivas-Torres, M. Fernandez-Mazuecos, P. Vargas, R. McCauley, G. Petersen, , M. D. Martin

This study characterizes the genomic basis of the plant island syndrome in Darwin's giant daisies by analyzing the genome of Scalesia atractyloides, identifying subgenomes, polyploidization events, and genes under selection.

bioRxiv · Jan 26, 2022Evolutionary Biology

Actin dynamics regulation by TTC7A/PI4KIIIα axis limits DNA damage and cell death during leukocyte migration

T. Gajardo, M. Lo, M. Bernard, C. Leveau, M.-T. El-Daher, M. Kurowska, G. Le Lay, D. Moshous, B. Neven, A. Fischer, G. Menasche, G. de Saint Basile, P. Vargas, F. E. Sepulveda

This study shows TTC7A deficiency impairs leukocyte migration, leading to DNA damage and cell death during chemotaxis in dense environments.

bioRxiv · Oct 14, 2021 · PreprintImmunology

Pinching the cortex of live cells reveals thickness instabilities caused by Myosin II motors

V. LAPLAUD, N. Levernier, J. Pineau, M. San-Roman, L. Barbier, P. J. Saez, A.-M. Lennon-Dumenil, P. Vargas, K. Kruse, O. DU ROURE, M. Piel, J. Heuvingh

The paper measures cortical thickness in live cells using magnetic beads and finds it is dynamic and fluctuates due to actomyosin contractility.

bioRxiv · Sep 28, 2020Biophysics

HIF2α is a Direct Regulator of Neutrophil Motility

S. Sormendi, M. Deygas, A. Sinha, A. Krueger, I. Kourtzelis, G. Le Lay, M. Bernard, P. Saez, M. Gerlach, K. Franke, A. Meneses, M. Kraeter, A. Palladini, J. Guck, U. Coskun, , B. Wielockx

This study identifies HIF2α as a regulator of neutrophil motility through the PHD2-HIF2-RhoA axis, enhancing migration in hypoxic environments during inflammation.

bioRxiv · Jun 5, 2020Immunology

Genomic evidence for recurrent genetic admixture during domestication mediterranean olive trees (Olea europaea).

I. Julca, M. Marcet-Houben, F. Cruz, J. Gomez-Garrido, B. S. Gaut, C. M. Diez, I. G. Gut, T. S. Alioto, P. Vargas, T. Gabaldon

This study analyzes genomic data from olive trees to show genetic admixture during domestication and identifies selected genes related to stress response and development.

bioRxiv · Mar 28, 2020Evolutionary Biology

A snapshot of progenitor-derivative speciation in action in Iberodes (Boraginaceae)

A. Otero, P. Vargas, V. Valcarcel, M. Fernandez-Mazuecos, P. Jimenez-Mejias, A. L. Hipp

The paper studies speciation patterns in Iberodes, revealing repeated progenitor-derivative speciation and its interaction with ecological and geographical factors.

bioRxiv · Dec 11, 2019 · PreprintEvolutionary Biology

Profilin and formin constitute a pacemaker system for robust actin filament growth

J. Funk, F. Merino, L. Venkova, P. Vargas, S. Raunser, M. Piel, P. Bieling

This study shows that profilin and formin work together to control actin filament growth rates, making them resilient to changes in soluble actin concentrations.

bioRxiv · Aug 15, 2019Biochemistry

Glioma cell migration in confined microchannels via a motor-clutch mechanism

L. S. Prahl, M. R. Stanslaski, P. Vargas, M. Piel, D. J. Odde

This study investigates glioma cell migration in confined microchannels using a motor-clutch mechanism, showing that parameters from 2D experiments predict 1D migration behaviors.

bioRxiv · Dec 29, 2018Biophysics

Three-Dimensional Histology of Whole Zebrafish by Sub-Micron Synchrotron X-ray Micro-Tomography

Y. Ding, D. J. Vanselow, M. A. Yakovlev, S. R. Katz, A. Y. Lin, D. P. Clark, P. Vargas, X. Xin, J. E. Copper, V. A. Canfield, K. C. Ang, Y. Wang, X. Xiao, F. De Carlo, D. B. van Rossum, , K. C. Cheng

This paper develops a method to create 3D histological images of whole zebrafish using synchrotron X-ray micro-tomography, enabling cellular-resolution phenotyping without sectioning.

bioRxiv · Aug 25, 2018Pathology

Phylogenomics of the olive tree (Olea europaea) disentangles ancient allo- and autopolyploidizations in Lamiales.

I. Julca, M. Marcet-Houben, P. Vargas, T. Gabaldon

The paper uses phylogenomics to identify and distinguish between ancient allo- and autopolyploidization events in the olive tree lineage.

bioRxiv · Jul 13, 2017Evolutionary Biology