Author

C. Mim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Yaron· 1 shared G. Dahl· 1 shared J. Guez-Haddad· 1 shared J. Wang· 1 shared M. Dessau· 1 shared M. Hons· 1 shared M. N. Isupov· 1 shared M. Sporny· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. Yaron

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2 papers

Recent·Most cited

A metastasis-associated Pannexin1 mutant (Panx11-89) forms a minimalist ATP release channel

J. Wang, C. Mim, G. Dahl, R. Barro-Soria

This study shows that the Panx11-89 mutant forms a functional ATP release channel independently of wild-type Panx1, with conserved structure-function features and sensitivity to inhibitors.

bioRxiv · Mar 12, 2024 · PreprintBiophysics

The Structural Basis for SARM1 Inhibition, and Activation Under Energetic Stress

M. Sporny, J. Guez-Haddad, T. Khazma, A. Yaron, M. Dessau, C. Mim, M. N. Isupov, R. Zalk, M. Hons, Y. Opatowsky

This paper presents cryo-EM structures of SARM1 showing how NAD+ inhibits its NADase activity and how NAD+ depletion activates it, leading to cell death.

bioRxiv · Aug 5, 2020Biochemistry