C. O'Neill

This study investigates how integrin-ligand combinations affect cardiomyocyte adhesion, traction forces, and mechanosignalling in healthy and fibrotic ECM environments.

This study shows MAIT cells are altered in Hidradenitis Suppurativa patients, with reduced frequencies and IL-17 bias, and highlights RORyt inhibition as a potential therapy.

This study identifies a MYC-SLC7A5-Glycolysis metabolic axis critical for MAIT cell proliferation, showing its impairment in obesity.

This study shows that alpha-synuclein treatment in rats alters their faecal virome, with changes persisting over five months and influenced by LPS.

The paper examines subsurface soil microbial communities across 20 U.S. profiles, finding decreased diversity and distinct taxa at depth, including the dominant Dormibacteraeota phylum, and identifies genomic traits enabling survival in oligotrophic conditions.

The paper translates genetic insights from Arabidopsis to oilseed rape to reduce seed loss from pod shatter, increasing yield through gene mutation and software development.