Author

C. P. Herlihy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

E. A. Crowley· 2 shared A. L. Manning· 1 shared A. Manning· 1 shared N. Hermance· 1 shared N. M. Hermance· 1 shared S. Hahn· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersCell Biology

E. A. Crowley

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2 papers

Recent·Most cited

Cell BiologybioRxivJun 14, 2021

Suv420 enrichment at the centromere limits Aurora B localization and function

C. P. Herlihy, S. Hahn, E. A. Crowley…·A. Manning

This study shows that Suv420 enrichment at centromeres reduces Aurora B localization, leading to mitotic errors and chromosome missegregation, with implications for cancer.

DOI 10.1242/jcs.249763

humanChIP-seq

𝕏 PostBluesky

Cancer BiologybioRxivJul 10, 2020

Suppression of chromosome instability limits acquired drug resistance

E. A. Crowley, N. M. Hermance, C. P. Herlihy, A. L. Manning

This study shows that suppressing chromosome instability reduces acquired drug resistance in non-small cell lung cancer by altering molecular mechanisms, without affecting tumor growth.

DOI 10.1158/1535-7163.mct-22-0263

humanbulk RNA-seq

𝕏 PostBluesky