C. S. Mitsiades

The paper uses single-cell and genome-scale functional genomics to study how blood cancer cells evade NK cells, identifying key genes and pathways involved in resistance and sensitivity.

The paper identifies aberrant chromatin activation as a common mechanism driving the malignant phenotype in multiple myeloma.

This paper validates tofacitinib as an effective anti-myeloma therapy by reversing bone marrow microenvironment-driven growth signals in vitro and in vivo.