Author

M. Ghait

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

M. Bauer· 2 shared S. D. Deshmukh· 2 shared A. Press· 1 shared A. Ramoji· 1 shared B. Goehrig· 1 shared B. Loeffler· 1 shared C. Beemelmanns· 1 shared C. Sponholz· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

M. Bauer

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Gram-positive bacteria secrete RNA aptamers to activate human STING for IL-1β release.

S. N. Duduskar, M. Ghait, M. Westermann, H. Guo, A. Ramoji, C. Sponholz, B. Goehrig, T. Bruns, U. Neugebauer, J. Popp, L. P. N. Tuchscherr, B. Loeffler, N. Ueberschaar, C. Beemelmanns, M. Singer, , S. D. Deshmukh

This study identifies RNA aptamers secreted by Gram-positive bacteria that activate the STING pathway to induce IL-1β release in human macrophages.

bioRxiv · Jul 21, 2021 · PreprintImmunology

RIPK3 promoter hypermethylation in hepatocytes protects from bile acid induced inflammation and necroptosis

J. Hoff, L. Xiong, T. Kammann, S. Neugebauer, J. M. Micheel, M. Ghait, S. D. Deshmukh, A. Press, M. Bauer, N. Gassler

The paper shows that RIPK3 promoter hypermethylation in hepatocytes reduces RIPK3 expression, protecting against bile acid-induced inflammation and necroptosis, but RIPK3 induction may signal danger in cholestatic liver diseases.

bioRxiv · Jan 15, 2021 · PreprintBiochemistry