FoxO factors preserve airway epithelial homeostasis by coordinating adaptive stress responses
K. Uliczka, J. M. Bossen, U. Zissler, C. Fink, X. Niu, M. Pieper, R. D. Prange, C. Vock, C. Wagner, M. Knop, A. Abdelsadik, S. Franzenburg, I. Bruchhaus, M. Wegmann, C. B. Schmidt-Weber, , T. Roeder
The paper shows FoxO factors in Drosophila, mouse, and human airway epithelial cells respond to stressors by nuclear translocation, with FoxO-dependent stress pathways altered in asthma across species.
bioRxiv · Jan 31, 2024 · PreprintPhysiology