Author

C.-F. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. L. Gonye· 1 shared A. Thomas· 1 shared A. Zimmermann· 1 shared B. Elenbaas· 1 shared C. W. Schultz· 1 shared C.-J. Kim· 1 shared D. Atkinson· 1 shared D. Wangsa· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. L. Gonye

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2 papers

Recent·Most cited

ATR inhibition augments the efficacy of lurbinectedin in small cell lung cancer

C. W. Schultz, Y. Zhang, R. Elmeskini, A. Zimmermann, H. Fu, Y. Murai, D. Wangsa, S. Kumar, N. Takahashi, D. Atkinson, L. K. Saha, C.-F. Lee, B. Elenbaas, P. Desai, R. Sebastian, , A. Thomas

This study shows that combining ATR inhibition with lurbinectedin improves efficacy in SCLC, particularly in MYC-driven non-neuroendocrine tumors.

EMBO Molecular Medicine · Aug 7, 2023Peer-reviewedCancer Biology

Nuclear morphology predicts cell survival to cisplatin chemotherapy

C.-J. Kim, A. L. Gonye, K. Truskowski, C.-F. Lee, R. Austin, K. J. Pienta, S. R. Amend

This study identifies nuclear morphology and functional characteristics associated with cancer cell survival after cisplatin chemotherapy, highlighting the role of the polyaneuploid cancer cell (PACC) state in treatment resistance.

bioRxiv · Sep 19, 2022Cancer Biology