Author

C.-T. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:organoid / primary culture· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. L. Sawyers· 2 shared C. Wu· 2 shared J. Garcia-Aguilar· 2 shared J. J. Smith· 2 shared J. Shia· 2 shared M.-J. Gubbels· 2 shared P. B. Paty· 2 shared P. B. Romesser· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

C. L. Sawyers

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Author profile →

4 papers

Recent·Most cited

A new immunocompetent rectal cancer model to study radiation therapy

J. K. Kim, C. Wu, M. Del Latto, Y. Gao, S.-H. Choi, M. Kierstead, C.-E. G. Sauve, C. Firat, A. C. Perez, J. Sillanpaa, C.-T. Chen, K. E. Lawrence, P. B. Paty, F. M. Barriga, J. Shia, , J. J. Smith

This paper introduces a mouse model of rectal cancer that mimics human tumor progression and radiation response for preclinical studies.

bioRxiv · Feb 7, 2022 · PreprintCancer Biology

The apical annuli of Toxoplasma gondii are composed of coiled-coil and signaling proteins embedded in the IMC sutures

K. Engelberg, C.-T. Chen, T. Bechtel, V. Sanchez Guzman, A. A. Drozda, S. Chavan, E. Weerapana, M.-J. Gubbels

This study identifies and characterizes apical annuli proteins in Toxoplasma gondii using BioID and SR-SIM, revealing their structural and functional roles in parasite replication and signaling.

Cellular Microbiology · Sep 10, 2019Peer-reviewedCell Biology

A rectal cancer model establishes a platform to study individual responses to chemoradiation

K. Ganesh, C. Wu, K. P. O'Rourke, M. Adileh, B. C. Szeglin, I. Wasserman, M. R. Marco, M. Shady, Y. Zheng, W. R. Karthaus, H. H. Won, S.-H. Choi, R. A. Pelossof, A. Barlas, E. Pappou, , J. J. Smith

This study develops a rectal cancer organoid model that mimics patient tumor responses to chemoradiation and metastasis in mice.

bioRxiv · May 22, 2019 · PreprintCancer Biology

TgCep250 is dynamically processed through the division cycle and essential for structural integrity of the Toxoplasma centrosome

C.-T. Chen, M.-J. Gubbels

This study identifies TgCep250 as a protein essential for maintaining the structural integrity of the Toxoplasma centrosome during the cell cycle, ensuring proper nuclear partitioning.

bioRxiv · Oct 3, 2018Microbiology