Author

C.-W. J. Lio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Almonte-Loya· 1 shared A. G. Freud· 1 shared A. Rao· 1 shared A. Saadey· 1 shared A. Varkey· 1 shared C. D. Eisele· 1 shared D. J. Wozniak· 1 shared D. M. Jones· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperImmunology

A. Almonte-Loya

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 18, 2022

Aiolos modulates the TFH and CD4-CTL differentiation programs via reciprocal regulation of the Zfp831/TCF-1/Bcl-6 axis and CD25

K. A. Read, D. M. Jones, S. Pokhrel…·K. J. Oestreich

This study identifies Aiolos as a regulator of TFH and CD4-CTL differentiation, showing it modulates the Zfp831/TCF-1/Bcl-6 axis and suppresses the cytotoxic gene program.

DOI 10.1101/2022.05.18.492485

mouseexperimental assay

ImmunologybioRxivPreprintSep 15, 2021

Epigenetic Remodeling by Vitamin C Potentiates the Differentiation of Mouse and Human Plasma Cells

H.-Y. Chen, A. Almonte-Loya, F.-Y. Lay…·C.-W. J. Lio

This study shows vitamin C enhances plasma cell differentiation in mouse and human B cells by epigenetic remodeling via TET enzymes and STAT3-dependent mechanisms.

DOI 10.1101/2021.09.15.460473

mousehuman

ImmunologybioRxivPreprintFeb 15, 2019

Loss of TET proteins in regulatory T cells unleashes effector function

X. Yue, C.-W. J. Lio, D. Samaniego-Castruita…·A. Rao

This study shows that loss of TET2 and TET3 in regulatory T cells leads to immune dysfunction and inflammation in mice.

DOI 10.1101/551093

mouseDNA methylation