NeurosciencebioRxivPreprint
α-synuclein aggregates induce c-Abl activation and neurodegeneration by a redox stress mechanism
Soumitra Ghosh, Seok Joon Won, Rebecca Fong…·Raymond A. Swanson
This study shows that α-synuclein aggregates cause c-Abl activation via redox stress, leading to neurodegeneration, and that N-acetyl cysteine can block this process in Parkinson's disease models.
1 citation