Author

Chiara Rignot

University of California, Irvine

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Evolutionary Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Approach:statistical model· 1

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Angela G. FleischmaniD· 1 shared Dominik WodarziD· 1 shared Natalia L. KomarovaiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperEvolutionary Biology

Angela G. FleischmanORCID

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Evolutionary BiologyProceedings of the National Academy of SciencesPeer-reviewedSep 9, 2024

Dynamically adjusted cell fate decisions and resilience to mutant invasion during steady state hematopoiesis revealed by an experimentally parameterized mathematical model

Natalia L. Komarova, Chiara Rignot, Angela G. Fleischman, Dominik Wodarz

The paper uses an experimentally parameterized mathematical model to show how hematopoietic stem cells dynamically adjust and resist mutant invasion during steady state hematopoiesis.

5 citations

mousestatistical model

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