Author

Chong Hwan Chang

Westlake University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

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Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Chensi Miao· 1 shared Fajie YuaniD· 1 shared Ge CheniD· 1 shared Geng LiiD· 1 shared Mingsun Sun· 1 shared Qianyue HuangiD· 1 shared Weikuan Liu· 1 shared Xiaoqi Fan· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Chensi Miao

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1 paper

Recent·Most cited

BioengineeringMolecular CellPeer-reviewedFeb 19, 2024

Protein language models-assisted engineering of Uracil-N glycosylase enables programmable T-to-G and T-to-C base editing

Yan He, Xibin Zhou, Chong Hwan Chang…·Xing Chang

This study uses protein language models to engineer a uracil-N-glycosylase variant for programmable T-to-G and T-to-C base editing, achieving high success rates in correcting genetic mutations in mice.

83 citationstop 1%

mouseCRISPR screen

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