Claudia Cavarischia-Rega

This study identifies Vlf1 as a vacuolar lipophagy regulator in S. cerevisiae, showing its localization to the vacuole and interaction with Atg15, with effects on autophagy levels.

The paper uses proximity labeling to identify proteins interacting with mitochondrial import complexes, revealing EXD2 as a TOM/SAM-associated factor at the mitochondrial outer membrane.

This study compares mitosis in 3D tumor spheroids and 2D monolayers, finding prometaphase delays and proteomic changes in spheroids.

This study shows that PINK1 regulates cholesterol homeostasis in human dopaminergic neurons by phosphorylating SCAP, and restoring cholesterol levels rescues defects in neurotransmitter uptake.

This study develops nanobodies to monitor Drp1, a mitochondrial fission factor, using proteomics, microscopy, and live-cell imaging techniques to study its dynamics in disease models.