Ana J. García‐Sáez

The paper investigates the role of mechanical forces in mitochondrial inner membrane extrusion and apoptotic pore growth using CLOSE microscopy.

The paper develops a fluorescent cGAMP biosensor to monitor cGAS-STING signaling dynamics in real-time and across different cellular contexts.

This study investigates how lipid oxidation affects membrane mechanics and pore formation by analyzing model membrane systems.

This study develops nanobodies to monitor Drp1, a mitochondrial fission factor, using proteomics, microscopy, and live-cell imaging techniques to study its dynamics in disease models.

This study identifies PINK1's role in regulating mitochondrial function, lipid metabolism, and dopamine homeostasis in dopaminergic neurons, showing that cholesterol depletion can reverse PINK1-related phenotypes.

This study shows that Bax mitochondrial residency, not oligomerization, is critical for apoptosis, using mutants in cell-free and cellular systems.