Author

D. Aldea

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1

Frequent Co-Authors

B. Kokalari· 2 shared Y. Atsuta· 2 shared Y. G. Kamberov· 2 shared A. Barlier· 1 shared A. Hall· 1 shared A. Nace· 1 shared B. Warder· 1 shared C. Stefan· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersEvolutionary Biology

B. Kokalari

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Author profile →

4 papers

Recent·Most cited

Deconvoluted methylation profiles discriminate between closely related melanocytic nevi

D. Aldea, N. Macagno, E. Marechal, M. Moreno, P. Romanet, M. Pertuit, J. Garcia, N. Degardin, S. Mallet, I. James, G. Captier, A. Barlier, H. C. Etchevers

The paper uses weighted whole-genome methylation analysis to distinguish between congenital and acquired melanocytic nevi.

bioRxiv · Jun 11, 2024Cancer Biology

Differential modularity of the mammalian Engrailed 1 enhancer network directs eccrine sweat gland development

D. Aldea, B. Kokalari, Y. Atsuta, H. L. Dingwall, Y. Zheng, A. Nace, G. Cotsarelis, Y. G. Kamberov

The paper identifies a conserved enhancer, ECE20, that regulates Engrailed 1 expression in both mouse and human skin and brain, while showing that ECE18 is lineage-specific and not required in mice.

bioRxiv · Sep 14, 2022Evolutionary Biology

An Engrailed1 enhancer underlies human thermoregulatory evolution

D. Aldea, Y. Atsuta, B. Kokalari, S. Schaffner, B. Warder, Y. G. Kamberov

The paper identifies a human-specific enhancer of the EN1 gene that increases eccrine sweat gland density, linking it to human thermoregulatory evolution.

bioRxiv · Aug 22, 2020 · PreprintEvolutionary Biology

FDA-ARGOS: A Public Quality-Controlled Genome Database Resource for Infectious Disease Sequencing Diagnostics and Regulatory Science Research

H. Sichtig, T. Minogue, Y. Yan, C. Stefan, A. Hall, L. Tallon, L. Sadzewicz, S. Nadendla, W. Klimke, E. Hatcher, M. Shumway, D. Aldea, J. Allen, J. Koehler, T. Slezak, , U. Scherf

The paper introduces FDA-ARGOS, a quality-controlled genome database for infectious disease sequencing, and demonstrates its use in diagnostics and validation.

bioRxiv · Nov 29, 2018 · PreprintMicrobiology