Author

D. C. Thomas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 3 Immunology· 2 Biochemistry· 1 Cell Biology· 1 Evolutionary Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 4 Research Focus:differential expression· 3 Research Focus:ecology & biodiversity· 3 Approach:statistical model· 3 Research Focus:benchmarking· 2 Assay:whole-genome sequencing· 2 Approach:benchmark study· 1

Frequent Co-Authors

B. A. Roy· 2 shared L. O. Randzavola· 2 shared R. Vandegrift· 2 shared A. A. Kulik· 1 shared A. Bateman· 1 shared A. Haffenden· 1 shared A. Mariscal Chavez· 1 shared A. O. Speak· 1 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersEcology

B. A. Roy

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

A disease-associated gene desert orchestrates macrophage inflammatory responses via ETS2

C. T. Stankey, C. Bourges, T. Turner-Stokes, A. P. Piedade, C. Palmer-Jones, I. Papa, M. Silva dos Santos, L. O. Randzavola, L. Speidel, E. C. Parkes, W. Edwards, A. P. Rochford, C. Murray, J. I. MacRae, P. Skoglund, , J. C. Lee

The paper identifies ETS2 as a master regulator of macrophage inflammatory responses linked to a disease-associated gene desert and shows how modulating this pathway could improve treatment of inflammatory diseases.

Nature · Jun 5, 2024Peer-reviewedImmunology

Reversible restriction of electron flow across cytochrome b6f in dark acclimated cells limited for downstream electron sinks

S. Saroussi, P. Redekop, D. Karns, D. C. Thomas, T. M. Wittkopp, A. R. Grossman, M. C. Posewitz

This paper identifies a reversible restriction of electron flow at the cytochrome b6f complex in dark-acclimated Chlamydomonas reinhardtii cells under nitrogen limitation, preventing photodamage to photosystems.

bioRxiv · Oct 4, 2022 · PreprintPlant Biology

Evidence for alternate stable states in an Ecuadorian Andean Cloud Forest

A. Mariscal Chavez, D. C. Thomas, A. Haffenden, R. Manobanda, L. Duvauchelle, W. Defas, M. Angel Chinchero, J. D. Simba Larco, E. Jaramillo, B. A. Roy, M. Peck

The paper analyzes historical vegetation data from an Ecuadorian cloud forest to show that natural disturbances lead to resilient forest states, while anthropogenic disturbances create alternate stable states with distinct tree communities.

bioRxiv · Nov 26, 2021Ecology

EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling

L. O. Randzavola, P. M. Mortimer, E. C. Garside, E. R. Dufficy, A. Schejtman, G. Roumelioti, L. Yu, M. Pardo, K. Spirohn, C. Tolley, C. Brandt, K. Harcourt, E. Nichols, M. Nahorski, G. Woods, , D. C. Thomas

This study identifies EROS as a chaperone essential for gp91phox maturation and P2X7 receptor function, revealing its role in immune responses and infection resistance.

bioRxiv · Sep 14, 2021Immunology

A Library Of Induced Pluripotent Stem Cells From Clinically Well-Characterized, Diverse Healthy Human Individuals

C. Schaniel, P. Dhanan, B. Hu, Y. Xiong, T. Raghunandan, D. M. Gonzalez, S. L. D'Souza, A. Yadaw, J. Hansen, G. Jayaraman, B. Mathew, M. Machado, S. Berger, J. Tripodi, V. Najfeld, , R. Iyengar

The paper generates and characterizes a diverse library of hiPSCs from healthy humans for use in disease modeling and drug response studies.

bioRxiv · Oct 29, 2020Cell Biology

Crystal structure and molecular dynamics of human POLDIP2, a multifaceted adaptor protein in metabolism and genome stability

A. A. Kulik, K. K. Maruszczak, D. C. Thomas, N. L. A. Nabi, M. Carr, R. J. Bingham, C. D. O. Cooper

This study presents the crystal structure and molecular dynamics of POLDIP2, revealing its structural features and dynamic regions critical for protein interactions in metabolism and genome stability.

bioRxiv · Jul 24, 2020Biochemistry

An agent-based model of the Foraging Ascomycete Hypothesis

D. C. Thomas, R. Vandegrift, B. Roy

The paper constructs an agent-based model to explore the ecological advantages of viaphytism in fungal dispersal strategies under different environmental conditions.

bioRxiv · Feb 25, 2020Ecology

The soursop genome and comparative genomics of basalangiosperms provide new insights on evolutionaryincongruence

J. S. Strijk, D. Hinsinger, M. Roeder, L. Chatrou, T. Couvreur, R. Erkens, H. Sauquet, M. Pirie, D. C. Thomas, K. Cao

The paper presents the soursop genome and uses phylogenomic analysis to resolve angiosperm relationships, finding magnoliids as sister to monocots and eudicots.

bioRxiv · May 17, 2019 · PreprintEvolutionary Biology

New mining concessions will severely decrease biodiversity and ecosystem services in Ecuador

B. A. Roy, M. Zorrilla, L. Endara, D. C. Thomas, R. Vandegrift, J. M. Rubenstein, T. Policha, B. Rios-Touma

The paper assesses the impact of new mining concessions on biodiversity and ecosystem services in Ecuador's protected areas.

Tropical Conservation Science · Jun 19, 2018Peer-reviewedEcology