Author

D. Heidenreich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

O. Fedorov· 3 shared S. Knapp· 3 shared A. Chaikuad· 2 shared M. Moustakim· 2 shared P. E. Brennan· 2 shared C. H. Arrowsmith· 1 shared D. Merk· 1 shared G. Deblois· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

O. Fedorov

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivNov 9, 2019

Structural insights into interaction mechanisms of alternative piperazine-urea YEATS domain binders in MLLT1

X. Ni, D. Heidenreich, T. Christott…·A. Chaikuad

The paper characterizes piperazine-urea derivatives as acetyl/acyl-lysine mimetics for MLLT1 and reveals distinct interaction mechanisms through crystal structures.

DOI 10.1021/acsmedchemlett.9b00460

structural biologyexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivNov 8, 2018

A structure-based approach towards identification of inhibitory fragments for eleven-nineteen-leukemia protein (ENL) YEATS domain

D. Heidenreich, M. Moustakim, J. Schmidt…·S. Knapp

The paper identifies inhibitory fragments targeting the ENL YEATS domain using crystallography, providing starting points for chemical probe development.

DOI 10.1021/acs.jmedchem.8b01457

protein structureexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivAug 14, 2018

A Chemical Toolbox for the Study of Bromodomains and Epigenetic Signaling

Q. Wu, D. Heidenreich, S. Zhou…·S. Knapp

The paper presents a set of 25 chemical probes targeting human bromodomains and demonstrates their utility in studying muscle cell differentiation and triple negative breast cancer.

DOI 10.1038/s41467-019-09672-2

humanexperimental assay

𝕏 PostBluesky