Cell BiologybioRxiv
BRCA1 Mediated Homologous Recombination and S Phase DNA Repair Pathways Restrict LINE-1 Retrotransposition in Human Cells
X. Sun, P. Mita, D. J. Kahler…·J. D. Boeke
This study identifies BRCA1 and other DNA repair factors that suppress LINE-1 retrotransposition in human cells by affecting retrotransposition frequency and ORF2 protein translation.
DOI 10.1038/s41594-020-0374-z