Author

D. Kleiner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

F. Shmulevich· 2 shared R. Zarivach· 2 shared S. Bershtein· 2 shared A. Goncearenco· 1 shared A. R. Banday· 1 shared A. R. Panchenko· 1 shared A. Rajan· 1 shared A. Shahar· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

F. Shmulevich

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SAMase of bacteriophage T3 inactivates E. coli methionine S-adenosyltransferase by forming hetero-polymers

H. Simon-Baram, D. Kleiner, F. Shmulevich, R. Zarivach, R. Zalk, H. Tang, F. Ding, S. Bershtein

This paper shows that bacteriophage T3's SAMase degrades SAM and inhibits E. coli's MAT by forming hetero-polymers, leading to metabolic disruption.

bioRxiv · May 5, 2021Microbiology

The inter-dimeric interface controls function and stability of Ureaplasma urealiticum methionine S-adenosyltransferase

D. Kleiner, F. Shmulevich, R. Zarivach, A. Shahar, M. Sharon, G. Ben-Nissan, S. Bershtein

This study shows that the inter-dimeric interface of U. urealiticum MAT regulates catalytic activity and structural stability through conformational changes induced by product binding.

bioRxiv · Jun 12, 2019Biochemistry

Integrated proteogenomic analysis of metastatic thoracic tumors identifies APOBEC mutagenesis and copy number alterations as drivers of proteogenomic tumor evolution and heterogeneity

N. Roper, S. Gao, T. K. Maity, A. R. Banday, X. Zhang, A. Venugopalan, C. M. Cultraro, R. Patidar, S. Sindiri, A. Goncearenco, A. R. Panchenko, R. Biswas, A. Thomas, A. Rajan, C. A. Carter, , U. Guha

bioRxiv · May 11, 2018Cancer Biology