GABRD promotes the progression of breast cancer through CDK1-dependent cell cycle regulation
Q. Shang, F. Ren, K. Feng…·X. Wang
This study shows GABRD promotes breast cancer progression by regulating the cell cycle through CDK1 interaction.
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14 papers
Recent·Most cited
Q. Shang, F. Ren, K. Feng…·X. Wang
This study shows GABRD promotes breast cancer progression by regulating the cell cycle through CDK1 interaction.
X. Chen, S. Sun, X. Han…·L. Wang
This study compares multi-omics data across three plant sources of Amomi Fructus to identify genetic and transcriptomic differences, including gene flow and metabolic variation between populations.
K. Zhang, L. Zhang, N. Chen, J. Yue
The paper identifies G42 as a lysosomal calcium mobilizer that inhibits autophagy and viral infections by alkalizing lysosomal pH and blocking autophagosome-lysosome fusion.
H. Mou, J. Yue, Y. Jin…·S. Beyaz
This study shows CRISPR/Cas9 can induce exon skipping in β-catenin, creating gain-of-function mutations that drive distinct liver cancer subtypes in mice and are found in human HCC patients.
X. Wang, M. Hu, Y. Jin…·H. Ren
The paper analyzes SARS-CoV-2 genome sequences to show mutation sweeps driven by emerging variants, which may prolong the pandemic and challenge control efforts.
R. I. Krutilina, H. C. Playa, D. L. Brooks…·T. N. Seagroves
This study identifies CKB as a HIF-1 downstream gene promoting breast cancer metastasis and shows cyclocreatine therapy reduces invasion and enhances chemotherapy efficacy.
J. Dong, Z. Zhu, G. Cui…·X.-P. Liu
This study shows GC-derived exosomes induce EMT in peritoneal mesothelial cells via TGF-β1/Smads pathway, enhancing GC cell migration and adhesion.
The paper shows that Polycomb repressive complex 2 and Sin3 histone deacetylase complex work together to epigenetically control effector gene expression in Magnaporthe oryzae, regulating its pathogenicity.
J. Yue, C. Chen, X. Jing…·X. Zhang
This study develops a next-generation sequencing-based sterility test (NGSST) that reduces detection time to 48 hours and improves accuracy for biological products.
G. Biegert, T. Karpinets, X. Wu…·A. H. Klopp
This study compares 16S rRNA and whole-metagenome sequencing in cervical cancer patients, finding congruence in diversity metrics but discrepancies in genus-level abundances.
B. V. Chapman, T. Karpinets, T. T. Sims…·L. Colbert
This study uses whole exome sequencing to track cervical cancer mutations during chemoradiation, finding that CDK4/CDK6/cyclin D1-related mutations persist or increase, suggesting radiation resistance.
Y. Wang, T. Song, K. Li…·L. Liang
This study identifies subtype-specific influenza A virus-host protein interactions that correlate with different pathogenic outcomes.