The DAXX-SREBP axis promotes oncogenic lipogenesis and tumorigenesis
I. Mahmud, G. Tian, J. Wang, J. Lewis, A. Waddell, M. L. Lydon, L. Y. Zhao, J.-L. Li, H. T. Purayil, Z. Huo, Y. Daaka, T. J. Garrett, D. Liao
This study identifies the DAXX-SREBP axis as a driver of lipogenesis and tumorigenesis by showing its role in activating lipogenic gene expression and promoting tumor growth.
bioRxiv · Dec 31, 2020 · PreprintCancer Biology