Author

L. Joannas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

B. Demarco· 2 shared J. Henao-Mejia· 2 shared P. Broz· 2 shared A. A. DeLaney· 1 shared A. Alloatti· 1 shared B. C. Schaefer· 1 shared B. L. Lee· 1 shared C.-A. Assenmacher· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

B. Demarco

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genetic targeting of Card19 is linked to disrupted Ninj1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection

E. Bjanes, R. G. Sillas, R. Matsuda, B. Demarco, T. Fettrelet, A. A. DeLaney, O. S. Kornfeld, B. L. Lee, E. M. Rodriguez Lopez, D. Grubaugh, M. A. Wynosky-Dolfi, N. H. Philip, E. Krespan, D. Tovar, L. Joannas, , I. E. Brodsky

This study shows that genetic targeting of Card19 disrupts Ninj1 expression, impairs macrophage cell lysis, and increases susceptibility to Yersinia infection.

bioRxiv · Mar 19, 2021 · PreprintImmunology

RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signalling

K. Chen, B. Demarco, R. Heilig, S. Ramos, J. Grayczyk, C.-A. Assenmacher, E. Radaelli, L. Joannas, J. Henao-Mejia, I. Brodsky, P. Broz

The paper shows that RIPK1 activates GSDME in neutrophils to promote anti-Yersinia defence through pyroptosis and IL-1β release.

bioRxiv · Jan 20, 2021Immunology

Small molecule enhancers of endosome-to-cytosol import augment anti-tumour immunity

P. Kozik, M. Gros, D. N. Itzhak, L. Joannas, J. G. Magalhaes, A. Alloatti, E. Del Nery, G. H. Borner, S. Amigorena

The paper identifies small molecule enhancers of endosome-to-cytosol antigen import that improve cross-presentation and anti-tumour immunity.

bioRxiv · May 5, 2020Immunology