Author

D. Nicolaou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Alag· 1 shared A. Lakhani· 1 shared A. Shafer· 1 shared E. Salvestrini· 1 shared J. O. Park· 1 shared L. C. Chen· 1 shared M. Khericha· 1 shared X. Chen· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

A. Alag

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1 paper

Recent·Most cited

BioengineeringbioRxivPreprintOct 1, 2020

Rational Tuning of CAR Tonic Signaling Yields Superior T-Cell Therapy for Cancer

X. Chen, M. Khericha, A. Lakhani…·Y. Y. Chen

This study shows that tuning CAR tonic signaling improves T-cell therapy efficacy by designing CARs with low but non-zero tonic signaling, enhancing anti-tumor activity in mouse models.

DOI 10.1101/2020.10.01.322990

mouseprotein structure

𝕏 PostBluesky