Author

C. Ceol

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:zebrafish· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. Guerin· 2 shared A. D. Southam· 1 shared A. E. Floru· 1 shared A. F. L. Hurlstone· 1 shared A. Gramann· 1 shared A. Jankevics· 1 shared A. K. Lam· 1 shared A. M. Venkatesan· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCancer Biology

M. Guerin

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Author profile →

4 papers

Recent·Most cited

Treg cells drive MYCN-mediated immunosuppression and tumor aggressiveness in high-risk neuroblastoma

X. Qin, A. K. Lam, X. Zhang, S. Sengupta, B. J. Iorgulescu, T. Zuo, A. E. Floru, G. K. Meara, k. Lloyd, L. A. Kwok, K. S. Smith, T. R. Nagaraju, R. Meijers, C. Ceol, C.-T. Liu, , H. Feng

This study shows Treg cells drive MYCN-mediated immunosuppression and tumor aggressiveness in high-risk neuroblastoma using human and zebrafish models.

bioRxiv · Oct 3, 2022 · PreprintCancer Biology

DGAT1 is a lipid metabolism oncoprotein that enables cancer cells to accumulate fatty acid while avoiding lipotoxicity

D. J. Wilcock, A. P. Badrock, R. Owen, M. Guerin, A. D. Southam, H. Johnston, S. Ogden, P. Fullwood, J. Watson, H. Ferguson, J. Haworth, D. A. Richardson, G. R. Lloyd, A. Jankevics, W. B. Dunn, , A. F. L. Hurlstone

This study identifies DGAT1 as an oncoprotein that enables cancer cells to accumulate fatty acids while avoiding lipotoxicity, promoting melanoma formation.

bioRxiv · Jun 23, 2020 · PreprintCancer Biology

Loss of prdm1a accelerates melanoma onset and progression

R. Iwanaga, B. Truong, K. Lambert, R. Vyas, D. Orlicky, Y. Shellman, A.-C. Tan, C. Ceol, K. Artinger

This study shows that loss of PRDM1 accelerates melanoma onset and progression in zebrafish, with reduced PRDM1 expression linked to poor patient survival in humans.

bioRxiv · Dec 20, 2019Cancer Biology

Regulation of melanocyte development by ligand-dependent BMP signaling underlies oncogenic BMP signaling in melanoma

A. Gramann, A. M. Venkatesan, M. Guerin, C. Ceol

This study shows that BMP signaling via GDF6 suppresses melanocyte differentiation in zebrafish, mirroring its oncogenic role in melanoma.

bioRxiv · Jul 19, 2019Cancer Biology