Author

D. R. Calabrese

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Ferre-D'Amare· 1 shared A. Shemesh· 1 shared D. Incarnato· 1 shared J. Arakawa-Hoyt· 1 shared J. R. Greenland· 1 shared J. S. Schneekloth· 1 shared K. Yazdani· 1 shared L. L. Lanier· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Ferre-D'Amare

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2 papers

Recent·Most cited

BiochemistrybioRxivJan 5, 2022

Investigating the NRAS 5' UTR as a Target for Small Molecules

S. Balaratnam, Z. R. Torrey, D. R. Calabrese…·J. S. Schneekloth

This study identifies a novel small molecule that binds to the NRAS mRNA G4 structure, showing in vitro translation inhibition but limited in vivo effects, highlighting transcript heterogeneity challenges.

DOI 10.1016/j.chembiol.2023.05.004

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivAug 3, 2021

Natural Killer cell division regulates FcεRIγ expression downstream of mTOR activity

A. Shemesh, D. R. Calabrese, J. Arakawa-Hoyt…·L. L. Lanier

The paper shows that NK cell division and mTOR activity regulate FcRγ expression, with rapamycin and TGFβ reducing FcRγ levels by suppressing division.

DOI 10.1084/jem.20220551

humanflow cytometry

𝕏 PostBluesky