K. Yazdani

The paper identifies a functional ligand for an RNA G-quadruplex in DHX15 mRNA using competitive microarray screening and shows it inhibits translation.

The paper uses a DNA microarray to study how proteins and small molecules bind to DNA i-motifs, finding that hnRNP K broadly recognizes iMs while others prefer G-quadruplexes.

This study introduces ROBIN, a large RNA-binding small molecule library, and uses machine learning to model RNA-binding chemical space.

This study identifies a novel small molecule that binds to the NRAS mRNA G4 structure, showing in vitro translation inhibition but limited in vivo effects, highlighting transcript heterogeneity challenges.