Author

D. Remillard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

A. R. Ramos· 1 shared A. T. Kedves· 1 shared B. Cravatt· 1 shared B. F. Cravatt· 1 shared B. Karakyriakou· 1 shared C. J. Ott· 1 shared D. Lazar· 1 shared E. Chin· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

A. R. Ramos

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities

Y. Zhang, D. Remillard, U. Onubogu, B. Karakyriakou, J. N. Asiaban, A. R. Ramos, K. Bowland, T. R. Bishop, C. J. Ott, M. Janiszewska, B. F. Cravatt, M. A. Erb

The paper identifies collateral synthetic lethality between HDAC1 and HDAC2 in cancer cells and shows that targeting HDAC2 can suppress tumor growth by disrupting the NuRD complex.

bioRxiv · May 30, 2022Cancer Biology

Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8

D. Remillard, N. A. Savage, A. T. Kedves, J. Paulk, X. Chen, F. J. Garcia, M. J. Romanowski, P. A. Horton, J. Murphy, M. Schirle, E. M. Harrington, M. B. Maxwell, H. T. Pham, I. Maksimovic, J. R. Thomas, W. C. Forrester

The paper identifies a novel interaction between BRD8 and the NuA4 complex using chemoproteomics and develops selective probes for BRD8.

bioRxiv · Feb 22, 2021Biochemistry

An activity-guided map of electrophile-cysteine interactions in primary human immune cells

E. Vinogradova, D. Lazar, R. Suciu, Y. Wang, G. Bianco, Y. Yamashita, V. Crowley, D. Remillard, K. Lum, G. Simon, E. Kemper, M. Lazear, S. Yin, M. Blewett, M. Dix, , B. Cravatt

The paper maps electrophile-sensitive cysteines in primary human T cells and shows how electrophilic compounds affect T cell activation through cysteine modification.

bioRxiv · Oct 17, 2019 · PreprintImmunology