Author

D. Repana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Assay:whole-exome sequencing· 2 Approach:benchmark study· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

F. D. Ciccarelli· 2 shared J. Nulsen· 2 shared L. Dressler· 2 shared M. Bortolomeazzi· 2 shared A. Acha-Sagredo· 1 shared A. Baulies· 1 shared A. Kucharska· 1 shared A. Rowan· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

F. D. Ciccarelli

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3 papers

Recent·Most cited

USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development

L. Novellasdemunt, A. Kucharska, A. Baulies, G. Vlachogiannis, D. Repana, A. Rowan, A. Suarez-Bonnet, F. Ciccarelli, N. Valeri, V. S. W. Li

This study shows that USP7 inactivation suppresses intestinal tumor development in APC-mutant mice but causes colitis with prolonged deletion and is effective against patient-derived cancer organoids.

bioRxiv · Sep 22, 2022Cancer Biology

Comparative assessment of genes driving cancer and somatic evolution.

L. Dressler, M. Bortolomeazzi, M. R. Keddar, H. Misetic, G. Sartini, A. Acha-Sagredo, L. Montorsi, N. Wijewardhane, D. Repana, J. Nulsen, J. Goldman, M. Pollit, P. Davis, A. Strange, K. Ambrose, F. D. Ciccarelli

The paper assesses genes driving cancer and somatic evolution, revealing gaps in driver gene compendiums and identifying conserved genes that promote clonal expansion without malignancy.

bioRxiv · Aug 31, 2021 · PreprintCancer Biology

The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens.

D. Repana, J. Nulsen, L. Dressler, M. Bortolomeazzi, S. Kuppili Venkata, A. Tourna, A. Yakovleva, T. Palmieri, F. D. Ciccarelli

The paper curates a comprehensive list of 2,372 cancer-related genes from 275 publications, including sequencing screens of 119 cancer types, and provides annotations on their properties.

bioRxiv · Dec 1, 2018Cancer Biology