Author

N. Valeri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

G. Vlachogiannis· 3 shared A. Acar· 2 shared A. Sottoriva· 2 shared G. D. Cresswell· 2 shared I. Spiteri· 2 shared L. Magnani· 2 shared A. Baulies· 1 shared A. Graudenzi· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

G. Vlachogiannis

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Author profile →

3 papers

Recent·Most cited

Epigenetic heritability of cell plasticity drives cancer drug resistance through one-to-many genotype to phenotype mapping

J. Fernandez-Mateos, S. Milite, E. Oliveira, G. Vlachogiannis, B. Chen, E. Yara, G. D. Cresswell, C. James, L. Patruno, G. Ascolani, A. Acar, T. Heide, I. Spiteri, A. Graudenzi, G. Caravagna, , A. Sottoriva

The paper shows how epigenetic heritability of cell plasticity contributes to cancer drug resistance through a one-to-many genotype-to-phenotype mapping.

bioRxiv · Nov 15, 2023 · PreprintCancer Biology

USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development

L. Novellasdemunt, A. Kucharska, A. Baulies, G. Vlachogiannis, D. Repana, A. Rowan, A. Suarez-Bonnet, F. Ciccarelli, N. Valeri, V. S. W. Li

This study shows that USP7 inactivation suppresses intestinal tumor development in APC-mutant mice but causes colitis with prolonged deletion and is effective against patient-derived cancer organoids.

bioRxiv · Sep 22, 2022Cancer Biology

Exploiting evolutionary herding to control drug resistance in cancer

A. Acar, D. Nichol, J. Fernandez, G. D. Cresswell, I. Barozzi, S. P. Hong, I. Spiteri, M. Stubbs, R. Burke, A. Stewart, G. Vlachogiannis, C. C. Maley, L. Magnani, N. Valeri, U. Banerji, A. Sottoriva

This paper demonstrates evolutionary herding in non-small cell lung cancer to control drug resistance by shifting clonal composition and inducing collateral sensitivity.

bioRxiv · Mar 4, 2019 · PreprintCancer Biology