Author

A. Strange

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Approach:benchmark study· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

J. Ito· 2 shared K. Sato· 2 shared The Genotype to Phenotype Japan (G2P-Japan) Consortium· 2 shared A. Acha-Sagredo· 1 shared A. Ensser· 1 shared A. Herrmann· 1 shared A. Maeva· 1 shared A. Potter· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

J. Ito

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A Protein Language Model for Exploring Viral Fitness Landscapes

J. Ito, A. Strange, W. Liu, G. Joas, S. Lytras, The Genotype to Phenotype Japan (G2P-Japan) Consortium, K. Sato

This paper introduces CoVFit, a protein language model that predicts SARS-CoV-2 variant fitness using spike protein sequences, identifying fitness-enhancing mutations and predicting emerging variants.

bioRxiv · Mar 15, 2024Microbiology

Quantitative Nanohistology of aging dermal collagen

A. Strange, A. Maeva, S. Huang, S. Siddiqui, P. Bastien, S. Aguayo, M. Vaez, H. Pollock, M. Ghibaudo, A. Potter, H. Pageon, L. Bozec

This study uses atomic force microscopy to analyze collagen fibrils in skin samples from different age groups and anatomical sites, identifying age-related structural biomarkers in dermal collagen.

bioRxiv · Mar 2, 2023 · PreprintBiophysics

ORF3c is expressed in SARS-CoV-2 infected cells and suppresses immune activation by inhibiting innate sensing

M. Mueller, A. Herrmann, S. Fujita, J. E. Kolberg, C. Kruth, A. Strange, M. Schneider, J. Ito, A. Ensser, The Genotype to Phenotype Japan (G2P-Japan) Consortium, K. Sato, D. Sauter

This study identifies ORF3c as an immune evasion factor of SARS-CoV-2 that suppresses innate sensing by inhibiting RIG-I and MDA5 signaling.

bioRxiv · Feb 27, 2023Microbiology

Comparative assessment of genes driving cancer and somatic evolution.

L. Dressler, M. Bortolomeazzi, M. R. Keddar, H. Misetic, G. Sartini, A. Acha-Sagredo, L. Montorsi, N. Wijewardhane, D. Repana, J. Nulsen, J. Goldman, M. Pollit, P. Davis, A. Strange, K. Ambrose, F. D. Ciccarelli

The paper assesses genes driving cancer and somatic evolution, revealing gaps in driver gene compendiums and identifying conserved genes that promote clonal expansion without malignancy.

bioRxiv · Aug 31, 2021 · PreprintCancer Biology

Citizen science, cells and CNNs - deep learning for automatic segmentation of the nuclear envelope in electron microscopy data, trained with volunteer segmentations

H. Spiers, H. Songhurst, L. Nightingale, J. de Folter, R. Hutchings, C. J. Peddie, A. Weston, A. Strange, S. Hindmarsh, C. Lintott, L. M. Collinson, M. L. Jones

This paper trains a deep learning model to automatically segment the nuclear envelope in electron microscopy data using volunteer annotations from a citizen science project.

bioRxiv · Jul 28, 2020Cell Biology