Author

A. Rowan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:clustering· 1

Frequent Co-Authors

A. Suarez-Bonnet· 2 shared A. Baulies· 1 shared A. K. Lagendijk· 1 shared A. Kucharska· 1 shared A. Nagano· 1 shared Argyr· 1 shared B. Almeida· 1 shared B. Bakker· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. Suarez-Bonnet

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Hyaluronic acid turnover controls the severity of Cerebral Cavernous Malformations in bioengineered human micro-vessels

T. E. Yordanov, M. A. E. Martinez, T. Esposito, J. B. Tefft, L. I. Labzin, S. J. Stehbens, A. Rowan, B. M. Hogan, C. S. Chen, J. Lauko, A. K. Lagendijk

This study shows that HA turnover in ECM affects CCM severity in 3D microfluidic models, independent of KLF2/4.

bioRxiv · Mar 27, 2023 · PreprintCell Biology

USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development

L. Novellasdemunt, A. Kucharska, A. Baulies, G. Vlachogiannis, D. Repana, A. Rowan, A. Suarez-Bonnet, F. Ciccarelli, N. Valeri, V. S. W. Li

This study shows that USP7 inactivation suppresses intestinal tumor development in APC-mutant mice but causes colitis with prolonged deletion and is effective against patient-derived cancer organoids.

bioRxiv · Sep 22, 2022Cancer Biology

Targeted cancer therapy induces APOBEC fuelling the evolution of drug resistance

D. R. Caswell, M. K. Mayekar, P. Gui, E. K. Law, N. I. Vokes, C. M. Ruiz, M. Dietzen, M. Angelova, C. Bailey, O. Pich, B. Bakker, W. Wu, T. J. Humpton, D. L. Kerr, W. Hill, , Argyr

This study shows that targeted cancer therapy induces APOBEC-mediated mutagenesis, promoting drug resistance by increasing genetic diversity through mechanisms involving NF-κB activation and reduced DNA repair.

bioRxiv · Dec 18, 2020Cancer Biology

Escape from nonsense mediated decay associates with anti-tumor immunogenicity

K. Litchfield, J. Reading, E. Lim, H. Xu, P. Liu, M. Al-Bakir, S. Wong, A. Rowan, S. Funt, T. Merghoub, M. Lauss, I. M. Svane, G. Jonsson, J. Herrero, J. Larkin, , C. Swanton

This study identifies NMD-escape fs-indels as a biomarker associated with improved response to immunotherapy in melanoma patients.

bioRxiv · Nov 14, 2019Cancer Biology