Author

D. Sims

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Mattison· 1 shared A. Protheroe· 1 shared A. Ryan· 1 shared A. Sreedasyam· 1 shared B. McKinley· 1 shared B. Weers· 1 shared C. Loveday· 1 shared C. Palles· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPlant Biology

A. Mattison

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3 papers

Recent·Most cited

Single-cell analysis of signalling and transcriptional responses to type I interferons

R. E. Rigby, K. Rue-Albrecht, D. Sims, J. Rehwinkel

This study examines how different type I interferons affect signaling and gene expression in human immune cells, finding that responses vary in magnitude but not qualitatively.

bioRxiv · Jul 3, 2023Immunology

Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression and drug response

P. Zhang, I. Kitchen-Smith, L. Xiong, G. Stracquadanio, K. Brown, P. Richter, M. Wallace, E. Bond, N. Sahgal, S. Moore, S. Nornes, S. De Val, M. Surakhy, D. Sims, X. Wang, , G. Bond

The paper investigates interactions between germline and somatic variants in the p53 pathway to show their combined effects on cancer risk, progression, and treatment response.

bioRxiv · Nov 9, 2019Cancer Biology

The Sorghum bicolor reference genome: improved assembly and annotations, a transcriptome atlas, and signatures of genome organization

R. F. McCormick, S. K. Truong, A. Sreedasyam, J. Jenkins, S. Shu, D. Sims, M. Kennedy, M. Amirebrahimi, B. Weers, B. McKinley, A. Mattison, D. Morishige, J. Grimwood, J. Schmutz, J. Mullet

This paper improves the Sorghum bicolor reference genome, annotates it, and constructs a transcriptome atlas, revealing genomic features and gene expression patterns across developmental stages.

bioRxiv · Feb 21, 2017Plant Biology