Author

D. Slade

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Approach:genetic perturbation / CRISPR· 2 Assay:imaging· 2

Frequent Co-Authors

L.-M. Appel· 3 shared A. Akalin· 2 shared I. Grishkovskaya· 2 shared K. Djinovic-Carugo· 2 shared V. Franke· 2 shared A. Dammermann· 1 shared A. E. Dick· 1 shared A. Kasiliauskaite· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

L.-M. Appel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Imaging the microscopic viscoelastic anisotropy in living cells

H. Keshmiri, D. Cikes, M. Samalova, L. Schindler, L.-M. Appel, M. Urbanek, I. Yudushkin, D. Slade, W. J. Weninger, A. Peaucelle, J. Penninger, K. Elsayad

This paper introduces BLAM, a technique to map high-frequency viscoelastic anisotropy in living cells, and applies it to study plant cell wall growth and mammalian nuclear mechanics.

bioRxiv · May 28, 2023 · PreprintBiophysics

The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators

L.-M. Appel, I. Grishkovskaya, J. Benedum, V. Franke, A. Polyansky, A. Neudolt, A. Wunder, B. Zagrovic, A. Akalin, K. Djinovic-Carugo, D. Slade

bioRxiv · Feb 26, 2022 · PreprintBiochemistry

PHF3 regulates neuronal gene expression through the new Pol II CTD reader domain SPOC

L.-M. Appel, V. Franke, M. Bruno, I. Grishkovskaya, A. Kasiliauskaite, U. E. Schoeberl, M. G. Puchinger, S. Kostrhon, E. Beltzung, K. Mechtler, G. Lin, A. Vlasova, M. Leeb, R. Pavri, A. Stark, , D. Slade

This study identifies PHF3 as a CTD-binding factor that regulates neuronal gene expression by inhibiting Pol II elongation and mRNA stability.

bioRxiv · Feb 11, 2020Biochemistry

Cep97 Is Required For Centriole Structural Integrity And Cilia Formation In Drosophila

J. Dobbelaere, M. Schmidt-Cernohorska, M. Huranova, D. Slade, A. Dammermann

This study shows Cep97 is essential for centriole length and cilia formation in Drosophila, with its function linked to microtubule acetylation and stability.

bioRxiv · Aug 20, 2019Cell Biology

PARP inhibition causes premature loss of cohesion in cancer cells

E. Kukolj, T. Kaufmann, A. E. Dick, R. Zeillinger, D. W. Gerlich, D. Slade

This study shows PARP inhibition causes premature cohesion loss in cancer cells during mitosis, leading to sister chromatid scattering, and identifies PARP1/2 entrapment at replication forks as a mechanism.

bioRxiv · Jun 22, 2017Cell Biology