Cav3.1 is a leucine sensor in POMC neurons mediating appetite suppression and weight loss
Anthony H. K. Tsang, Nicholas Heeley, Constanza Alcaino…·Clémence Blouet
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University of Cambridge
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
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Anthony H. K. Tsang, Nicholas Heeley, Constanza Alcaino…·Clémence Blouet
Anthony H. K. Tsang, Danaé Nuzzaci, Tamana Darwish…·Clémence Blouet
The paper identifies a neural circuit in the nucleus of the solitary tract (NTS) that suppresses feeding by inhibiting AgRP neurons through leucine sensing and leptin-receptor-expressing neurons.
Sara Kohnke, Brian Lam, Sophie A Buller…·Clémence Blouet
The paper shows that refeeding after fasting rapidly activates oligodendrocyte differentiation in the hypothalamic median eminence, altering extracellular matrix proteins and using mTORC1 signaling to monitor nutritional signals.