Author

David JA Wyllie

The University of Edinburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:rat· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Alexander J Edwards· 1 shared Chigdem Arslan· 1 shared Daniel W Hunter· 1 shared Hannah Kaese· 1 shared Jelena BaranoviciD· 1 shared Peter C Kind· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 6 mutual co-author links

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1 shared paperNeuroscience

Alexander J Edwards

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 12, 2026

Loss of GluN2A Selectively Impairs Excitatory Synaptic Integration in Hippocampal Somatostatin Interneurons

Daniel W Hunter, Hannah Kaese, Peter C Kind, David JA Wyllie

This study shows that GluN2A loss specifically impairs excitatory synaptic integration in hippocampal somatostatin interneurons, affecting EPSP decay and firing without impacting pyramidal or parvalbumin interneurons.

DOI 10.64898/2026.11.11.763692

ratelectrophysiology

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 10, 2026

Mechanism and subunit-dependence of disease-associated lurcher mutation in AMPA-type glutamate receptors

Alexander J Edwards, Chigdem Arslan, David JA Wyllie, Jelena Baranovic

This study investigates the functional impact of the lurcher mutation in AMPA receptors, showing subunit-dependent effects on receptor kinetics and drug response.

DOI 10.64898/2026.11.09.765263

mouseelectrophysiology

𝕏 PostBluesky